A piece of the puzzle: 8 autism-related mutations in 1 gene

(University of Southern California) Researchers discover a large number of clustered mutations in a single gene, TRIO, that disrupt the development of the brain's connections and likely contribute to the development of autism-spectrum disorders. The scientists also find that a sister gene linked to schizophrenia, KALRN, is inactive in early brain development, but becomes active in adolescence.